Cinnabarinic Acid, >=98% (HPLC)

Code: SML0096-25MG D2-231

Not available outside of the UK & Ireland.

Application

Cinnabarinic acid may be used in studies of the functions of components of the kynurenine metabolic pathway. It may be used to study it role as a metabotropic glu...


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$666.37 25MG
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Not available outside of the UK & Ireland.

Application

Cinnabarinic acid may be used in studies of the functions of components of the kynurenine metabolic pathway. It may be used to study it role as a metabotropic glutamate receptor (mGlu4R-specific) agonist.

Biochem/physiol Actions

Caspase Inducer; mGlu4R agonistCinnabarinic acid (CA) connects between initiation of the kynurenine pathway and immune tolerance that is used to prevent neuroinflammation.

Cinnabarinic acid is a kynurenine pathway metabolite of tryptophan, produced by the oxidation of 3-Hydroxyanthranilic acid. Cinnabarinic acid leads to loss of mitochondrial respiration and apoptosis, and has also been shown to be an mGlu4R-specific agonist.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorred to very dark red
formpowder
InChI keyFSBKJYLVDRVPTK-UHFFFAOYSA-N
InChI1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21)
Quality Level100
SMILES stringNC1=C(C(O)=O)C2=Nc3c(OC2=CC1=O)cccc3C(O)=O
solubilityDMSO: ≥4 mg/mL
storage conditiondesiccated
storage temp.2-8°C
Cas Number606-59-7
This product has met the following criteria to qualify for the following awards:



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