Not available outside of the UK & Ireland.
Application
Picrotoxinin has been used as an agonist of taste 2 receptor member 14 (TAS2R14) to perform an array-based bitter receptor screening assay and to study the effect of calcium buffering and calcium sensor type on its sensitivity.
Biochem/physiol Actions
GABAA receptor antagonist; binds to the GABA receptor-linked Cl− channel.
Picrotoxinin acts as a potent convulsant.
Features and Benefits
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General description
Picrotoxinin is a component of picrotoxin and can be derived from plants. It is a non-nitrogenous compound.
Other Notes
Active component of picrotoxin
Packaging
250 mg in glass bottle
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