Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Putrescine dihydrochloride has been used:as a bioactive amine standard in high-performance liquid chromatography (HPLC)as a component of hormone mix supplemented to Dulbecco′s modified eagle medium (DMEM) to study its effects on neural stem cellsas a supplement in DMEM for culturing of endometrial cancer cells
Biochem/physiol Actions
Putrescine is an aliphatic amine and is positively charged. It acts as a precursor of spermine and plays a role in polyamine biosynthesis. Putrescine is found in several plants, animals, and bacteria. It plays a role in cell proliferation and cell growth in Escherichia coli. Putrescine is a component of agrochemicals, surfactants, pharmaceuticals, polymers, and additives.
Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.
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