LP44, >= 98%( HPLC ), solide

Code: l9793-10mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

LP44 has been used as a 5-hydroxytryptamine (serotonin) receptor 7 (5-HT7) agonist to study its effects on mitochondria-mediated leucine-rich repeat and pyrin dom...


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Votre prix
$230.20 10MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

LP44 has been used as a 5-hydroxytryptamine (serotonin) receptor 7 (5-HT7) agonist to study its effects on mitochondria-mediated leucine-rich repeat and pyrin domain containing 3 (NLRP3) inflammasome activation.

Biochem/physiol Actions

LP44 is a high affinity 5-HT7 receptor agonist. Ki = 0.22 nM. LP44 displays selectivity over 5-HT1A and 5-HT2A receptors (200- and >1000-fold, respectively). LP44 induces relaxation of substance P-stimulated guinea pig ileum (EC50 = 2.56 µM).

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
formsolid
InChI keyDWGKCWWWKHCVDH-UHFFFAOYSA-N
InChI1S/C27H37N3OS.ClH/c1-32-26-15-7-6-14-25(26)30-20-18-29(19-21-30)17-8-2-3-16-27(31)28-24-13-9-11-22-10-4-5-12-23(22)24;/h4-7,10,12,14-15,24H,2-3,8-9,11,13,16-21H2,1H3,(H,28,31);1H
Quality Level100
SMILES stringCl.CSc1ccccc1N2CCN(CCCCCC(=O)NC3CCCc4ccccc34)CC2
solubilityH2O: ≥2 mg/mL, DMSO: >10 mg/mL
storage temp.2-8°C
Cas Number824958-12-5
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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