Equilin,

Code: E8126-100MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Equilin is the Mare estrogen and is majorly used in multi-estrogen drugs for hormone replacement therapy. It is synthesized in the microsomes of mare ...


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$141.35 100MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

Equilin is the Mare estrogen and is majorly used in multi-estrogen drugs for hormone replacement therapy. It is synthesized in the microsomes of mare placenta. It mediates estrogen receptor β (ERβ) expression resulting in the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) which favors monocytes adhesion in atherosclerosis. In vitro equilin inhibits 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) that catalyzes the conversion of estrone to 17β-estradiol.

Packaging

100 mg in poly bottle

1 g in poly bottle

assay≥98% (HPLC)
biological sourcesynthetic (organic)
formpowder
InChI keyWKRLQDKEXYKHJB-HFTRVMKXSA-N
InChI1S/C18H20O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3-5,10,14,16,19H,2,6-9H2,1H3/t14-,16+,18+/m1/s1
mp238-240 °C (lit.)
Quality Level100
shipped inambient
SMILES stringC[C@]12CC[C@H]3C(=CCc4cc(O)ccc34)[C@@H]1CCC2=O
solubilitychloroform: methanol (1:1): 40 mg/mL, clear, colorless to faintly yellow
sterilitynon-sterile
storage temp.room temp
technique(s)inhibition assay: suitable
Cas Number474-86-2
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