Dihydroeponemycin, >=98% (HPLC)

Code: D4321-5MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Dihydroeponemycin is an active derivative of eponemycin an antitumor antibiotic isolated from Streptomyces hygroscopicus. Dihydroeponemycin l...


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$1,260.04 5MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

Dihydroeponemycin is an active derivative of eponemycin an antitumor antibiotic isolated from Streptomyces hygroscopicus. Dihydroeponemycin labels the catalytic threonine residues of the immunoproteasome subunits LMP2 and LMP7 and the constitutive proteasome subunit X, while epoxomicin covalently modifies the N-terminal catalytic threonine residues of the constitutive proteasome (X and Z) and immunoproteasome (LMP7 and MECL1) subunits.

Packaging

1, 5 mg in glass bottle

assay≥98% (HPLC)
coloroff-white to light tan
formpowder
InChI keyIUDBVFIQSSOIDB-TWOQFEAHSA-N
InChI1S/C20H36N2O6/c1-13(2)7-5-6-8-17(25)21-16(10-23)19(27)22-15(9-14(3)4)18(26)20(11-24)12-28-20/h13-16,23-24H,5-12H2,1-4H3,(H,21,25)(H,22,27)/t15-,16-,20+/m0/s1
optical activity[α]/D ±35.7°
Quality Level100
SMILES stringCC(C)CCCCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(CO)CO1
solubilityDMSO: ≥1 mg/mL
storage temp.2-8°C
Cas Number126463-64-7
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