R-(+)-DIOA, >=98% (HPLC), solid

Code: D129-10MG D2-231

Not available outside of the UK & Ireland.

Application

R-(+)-DIOA has been used as a potassium/chloride K+-Cl- transport inhibitor to study its effects on:short circuit current (Isc) in rat semic...


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Your Price
$405.21 10MG
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Not available outside of the UK & Ireland.

Application

R-(+)-DIOA has been used as a potassium/chloride K+-Cl- transport inhibitor to study its effects on:short circuit current (Isc) in rat semicircular canal duct (SCCD) epitheliumuptake of grepafloxacin by THP-1 monocytesthe uptake of moxifloxacin by THP-1 monocytes

Biochem/physiol Actions

[(dihydroindenyl)oxy]acetic acid (DIOA) acts as a potent inhibitor of potassium/chloride (K+–Cl−)co-transporter. It does not exert its effects on bumetanimide-sensitive [Na+,K+,Cl-]-cotransport system.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite
formsolid
InChI keyYAWWQIFONIPBKT-FQEVSTJZSA-N
InChI1S/C20H24Cl2O4/c1-2-3-8-20(13-6-4-5-7-13)10-12-9-14(26-11-15(23)24)17(21)18(22)16(12)19(20)25/h9,13H,2-8,10-11H2,1H3,(H,23,24)/t20-/m0/s1
optical activity[α]27/D +18.1°, c = 0.7 in methanol(lit.)
Quality Level100
SMILES stringCCCC[C@]1(Cc2cc(OCC(O)=O)c(Cl)c(Cl)c2C1=O)C3CCCC3
solubilityethanol: soluble, 0.1 M NaOH: soluble, H2O: insoluble ﹤0.11 mg/mL, 0.1 M HCl: insoluble, DMSO: >20 mg/mL
Cas Number81166-47-4
This product has met the following criteria to qualify for the following awards:



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