8-(3-Chlorostyryl)caffeine, >=98% (HPLC), solid

Not available outside of the UK & Ireland.

Application

8-(3-Chlorostyryl)caffeine has been used as an adenosine A_2A receptor antagonist:to study its effects on levodopa (L-DOPA)-induced dopamine (DA) release in rat striatumto study its effect on the nuclear factorκ-light-chain-enhancer of activated B cells (NF-κB) activity in macrophagesto determine its effects on human umbilical vein endothelial cells (HUVECs)

Biochem/physiol Actions

8-(3-Chlorostyryl)caffeine is a selective adenosine A_2Areceptor antagonist and monoamine oxidase B (MAO B) inhibitor.

Caution

Photosensitive, store in the dark

Features and Benefits

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

25, 100 mg in glass bottle