Anti-Collagen III, N-Terminal antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Application

Anti-Collagen III antibody has been used in immunohistochemistry.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunohistochemistry (1 paper)

Biochem/physiol Actions

Collagens usually help in the development of fibrillar and microfibrillar networks of the extracellular matrix, basement membranes and structures of the extracellular matrix. Mutations in the COL3A1 gene results in vascular ehlers-danlos syndrome (vEDS). COL3A1 controls the expression and modulation of collagen.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Anti-Collagen III Antibody detects endogenous levels of total Collagen III protein.Collagen III is also termed as collagen type III α1 (COL3A1). It is a fibrillar collagen present in extensible connective tissues. COL3A1 spans around 44kb in length and has 52 exons. It is expressed in blood vessels and hollow organs. Collagen III gene is located on human chromosome 2q32.2.

Immunogen

The antiserum was produced against synthesized peptide derived from human Collagen III.Immunogen Range: 81-130

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.