Anticorps Anti - RAB11A produit dans la souris, immunoglobulin purifiée, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Ras-related protein Rab-11A (RAB11A), member RAS oncogene family, is involved in vesicle trafficking during recycling of endosomes. Overexpression of RAB11A leads to an increased collective cell invasion in colorectal carcinoma.RAB11A and its binding partners plays a crucial role in recycling of human β1-adrenergic receptor.

General description

Ras-related protein Rab-11A (RAB11A), member RAS oncogene family, is a GTP binding protein. RAB11A gene is located on human chromosome 15q21.3. RAB11A is expressed abundantly in tissues with high secretion.

Immunogen

RAB11A (NP_004654.1, 1 a.a. ~ 216 a.a) full-length human protein.SequenceMGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNVVPIHVPPTTENKPKVQCCQNI

Physical form

Solution in phosphate buffered saline, pH 7.4