Anti-NOTCH1 antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

NOTCH homolog-1 (NOTCH-1) is an integral part of the NOTCH signaling pathway, which regulates various cellular functions. NOTCH-1 enhances the invasion of cancer cells and mutations in the gene encoding it have been associated with chronic lymphocytic leukemia (CLL).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

NOTCH homolog-1 (NOTCH-1) is a transmembrane receptor.

Immunogen

synthetic peptide corresponding to residues 2170-2187 of human NOTCH1.

Physical form

solution in phosphate buffered saline, containing 0.02% sodium azide.