Anticorps Monoclonal Anti - CD81 produit en souris, clone M38, immunoglobulin purifié, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 1 µg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Biochem/physiol Actions

Cluster of differentiation 81 (CD81) has a role in membrane organization, cell-cell interactions, cellular fusion and protein trafficking. It is also involved in receptor clustering and signaling. CD81 is overexpressed in cancers.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

The antibody M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Cluster of differentiation 81 (CD81) is expressed on the oocyte surface. It consists of five large helical segments and belongs to the tetraspanin family. The gene encoding this protein is localized on human chromosome 11p15.5.

Immunogen

MOLT-4 (human T-ALL cell line)

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.