Anti-Synapsin1, N-Terminal antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Synapsin I (SYN1) plays an important role in neurotransmitter release, exocytosis of the synaptic vesicles, neurite elongation and synaptogenesis. Brain dysfunction occurs due to improper expression of synapsin I.

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General description

Anti-Synapsin1 Antibody detects endogenous levels of total Synapsin1 protein.Synapsin I (SYN1) is a synaptic vesicle associated protein. It is present in the central nervous system like olfactory bulb, cerebral cortex, hippocampus, basal ganglia, thalamus, hypothalamus, cerebellum, pons-medulla, spinal cord and posterior pituitary gland. SYN1 is found in the nucleus and cytoplasm of granule cells, and in the glomerular synaptic complex of the cerebellum. It is located in human chromosome Xp11.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human Synapsin1.Immunogen Range: 26-75

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.