Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
GAD1 gene (glutamate decarboxylase 1) participates in GABA (γ-aminobutyric acid) synthesis. Variations in GAD1 results in hyperactivity in attention-deficit/hyperactivity disorder. It is also characterized with childhood-onset schizophrenia and cortical gray matter volume loss.
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Features and Benefits
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General description
Anti-GAD1 antibody detects endogenous levels of total GAD1 protein.
GAD1 gene (glutamate decarboxylase 1) codes for a glutamic acid decarboxylase enzyme (GAD67), that is of 67kDa. It is mapped to human chromosome 2q31.1.
Immunogen
The antiserum was produced against synthesized peptide derived from human GAD1.Immunogen Range: 471-520
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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