Anti-ATF5, C-Terminal antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Activating transcription factor 5 (ATF5) participates in metabolite homeostasis, cellular proliferation, differentiation, apoptosis and regulation of the cell cycle. It controls neural progenitor cell and adipose-derived stem cell differentiation.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Anti-ATF5 Antibody detects endogenous levels of total ATF5 protein.

Activating transcription factor 5 (ATF5) belongs to the ATF/cAMP response element-binding protein family. It is an anti-apoptotic protein that has 282 amino acids and is located on human chromosome 19q13. It is expressed in various cancers like prostate, rectal, colon, endometrium, breast, ovary, pancreas, gastric etc.

Immunogen

The antiserum was produced against synthesized peptide derived from human ATF5.Immunogen Range: 221-270

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.