Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Cathepsin K has a role in bone resorption and remodeling. It has a triple helical collagen hydrolase activity. Mutations in the gene encoding this protein have been linked to pycnodysostosis.
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Features and Benefits
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General description
Procathepsin K is the inactive proenzyme of cathepsin K. Cathepsin K is a lysosomal cysteine protease and part of the papain cysteine protease family. It is expressed in osteoclasts. The gene encoding this protein is localized on human chromosome 1q21.
Immunogen
Peptide with sequence C-KTHRKQYNNKVDE from the internal region (near N-terminus) of the protein sequence according to NP_000387.1.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
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