Anti-TNFSF4 anticorps produit dans la souris, immunoglobulin purifiée, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

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General description

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. (provided by RefSeq)

Immunogen

TNFSF4 (NP_003317.1, 1 a.a. ~ 183 a.a) full-length human protein.SequenceMERVQPLEENVGNAARPRFERNKLLLVASVIQGLGLLLCFTYICLHFSALQVSHRYPRIQSIKVQFTEYKKEKGFILTSQKEDEIMKVQNNSVIINCDGFYLISLKGYFSQEVNISLHYQKDEEPLFQLKKVRSVNSLMVASLTYKDKVYLNVTTDNTSLDDFHVNGGELILIHQNPGEFCVL

Physical form

Solution in phosphate buffered saline, pH 7.4