Monoclonal Anti-ISL1 antibody produced in mouse, clone 2E7, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

Disclaimer

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General description

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. (provided by RefSeq)

Immunogen

ISL1 (NP_002193, 63 a.a. ~ 159 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEP

Physical form

Solution in phosphate buffered saline, pH 7.4