Anti-APPBP1 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

APPBP1 binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer′s disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPBP1 is required for cell cycle progression through the S/M checkpoint.

Immunogen

APPBP1 (NP_003896, 5-34)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human APPBP1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.