Anti-ART1 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

ADP-ribosyltransferase 1 (ART1) catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of Escherichia coli. This protein has been associated with colon carcinoma.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The amino acid sequence of ADP-ribosyltransferase 1 (ART1) consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. The gene encoding this protein is localized on human chromosome 11p15.4.

Immunogen

ART1 (NAR1_HUMAN, 19-53)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ART1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.