Anti-human igm

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Anti-Human IgM antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Ig μ chain C region is a protein encoded by the IGHM gene in humans and is expressed on the surface of T cells. It is associated with agammaglobulinemia-1. Immunoglobulin is expressed in epithelial cell and plays a role in growth and survival. IgG heavy chain is expressed in acute myeloid leukemia (AML). IgM derived from AML might be a novel AML-related molecule that is involved in leukemogenesis and AML progression. It may serve as a useful molecular marker for designing targeted therapy and monitoring minimal residual disease. Elevated levels of soluble IGM Ligand (sCD40L) were found in serum of patients with chronic spontaneous urticaria (CU).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Human IgM native protein.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.