Anti-Cytokératine monoclonale, anticorps pan - FITC produit dans la souris, clone C-11, immunoglobulin purifié, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Monoclonal Anti-Cytokeratin, pan−FITC antibody has been used in immunocytochemistry and has also been used to visualize lung epithelial cells.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunofluorescence (1 paper)Immunohistochemistry (1 paper)

Biochem/physiol Actions

Cytokeratins helps in subtyping several kinds of epithelial differentiation or for narrowing possible sites of origin for metastatic carcinomas. Cytokeratins may play an important role in transhepatic transport and canalicular secretion.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Cytokeratins are the intermediate filaments of endocrine cells. These proteins belong to the intermediate filament (10 nm) superfamily of cytoskeletal proteins. Cytokeratins are the largest and most complex group of intermediate filaments. The family consists of at least 30 proteins with molecular weights ranging from 40kDa to 68kDa.

Immunogen

keratin-enriched preparation from cultured human epidermoid carcinoma cell line A431.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.