2-BROMOPYRIDIN-3-YL SULFUROFLUORIDATE

Not available outside of the UK & Ireland.

Application

2-Bromopyridin-3-yl sulfurofluoridate can be used in the Pd-catalyzed Suzuki-Miyuara cross-coupling reaction. The fluorosulfate functionality was shown by Sharpless and coworkers to have distinct reactivity in comparison to other functional groups used in Suzuki-Miyuara reactions, such as bromides, chlorides and triflates. This inherent property provides a strong potential for selective Suzuki-Miyuara couplings for chemoselective reaction sequences.

Other Notes

Palladium-Catalyzed, Ligand-Free Suzuki Reaction in Water Using Aryl Fluorosulfates

Chemoselective Synthesis of Polysubstituted Pyridines from Heteroaryl Fluorosulfates

Packaging

500 mg in poly bottle