R-IMPP HYDROCHLORIDE

Code: SML2045-5MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

R-IMPP is a potent and selective inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) secretion that stimulates uptake of LDL-C in hepat...


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$103.66 5MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

R-IMPP is a potent and selective inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) secretion that stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin. R-IMPP binds selectively to human ribosomes and causes transcript-dependent inhibition of PCSK9 translation.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringO=C(CCC1=CC=C(OC)C=C1)N([C@H]2CNCCC2)C3=C(C=CC=C4)C4=CC=N3.[H]Cl
solubilityDMSO: 2 mg/mL, clear
storage temp.−20°C
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