SEL DE TÉTRASODIUM CANGRELOR

Name: SEL DE TÉTRASODIUM CANGRELOR
Brand: SIGMA-ALDRICH
SKU: sml2004-5mg
Price: 360.78 USD

Code: sml2004-5mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Cangrelor has been used as a purinergicreceptor P2Y12antagonist to study its effects on neuromedin U receptor 2 (NMUR2)-coupled Gαi pathway during platelet aggreg...

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Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Cangrelor has been used as a purinergicreceptor P2Y12antagonist to study its effects on neuromedin U receptor 2 (NMUR2)-coupled Gαi pathway during platelet aggregation.

Biochem/physiol Actions

Cangrelor is a potent and selective platelet P2Y12 antagonist. It is used as an intravenous antiplatelet drug to prevent formation of harmful blood clots in the coronary arteries.

Cangrelor is an analog of nonthienopyridine adenosine triphosphate. It has a therapeutic effect against reversible platelet inhibition.

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI key	COWWROCHWNGJHQ-OPKBHZIBSA-J
InChI	1S/C17H25Cl2F3N5O12P3S2.4Na/c1-43-5-3-23-12-9-13(26-15(25-12)44-4-2-16(20,21)22)27(7-24-9)14-11(29)10(28)8(38-14)6-37-42(35,36)39-41(33,34)17(18,19)40(30,31)32;;;;/h7-8,10-11,14,28-29H,2-6H2,1H3,(H,33,34)(H,35,36)(H,23,25,26)(H2,30,31,32);;;;/q;4*+1/p-4/t8-,10-,11-,14-;;;;/m1..../s1
SMILES string	O[C@@H]1[C@H](O)[C@@H](COP(OP(C(Cl)(Cl)P(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)O[C@H]1N(C=N2)C3=C2C(NCCSC)=NC(SCCC(F)(F)F)=N3
solubility	H₂O: 2 mg/mL, clear
storage temp.	−20°C

Certificat d'analyse Sigma

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

SEL DE TÉTRASODIUM CANGRELOR

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