ANTI-PHOSPHO - DPYSL2-T514 anticorps PRODU+amp;

Non disponible en dehors du Royaume-Uni et de l'Irlande

General description

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer′s disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding T514 of human DPYSL2

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.