Lipopolysaccharide; Ultra Pure; Salmonella minnesota R595 (Re)

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetStimulate Toll-like receptor-4 (TLR4) signaling in human cell lines

General description

Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing ≤0.3% proteins. LPS 595 (Re) has been shown to stimulate Toll-like receptor-4 (TLR4), but not TLR2, signaling in human cell lines.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Hirschfeld, M., et al. 2000. J. Immunol.165, 618.Tapping, R.I., et al. 2000. J. Immunol.165, 5780.Galanos, C., et al. 1969. Eur. J. Biochem.9, 245.

Packaging

1 mg in Plastic ampoule

Preparation Note

Warming to 37°C with intermittent vortexing or sonication may be required to achieve complete solubilization in H₂O.

Reconstitution

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months.

Warning

Toxicity: Harmful (C)