PROCARBAZINE HYDROCHLORIDE

Code: SML0036-10MG D2-231

Not available outside of the UK & Ireland.

Application

Procarbazine, an antineoplastic alkylating agent, may be used to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an anticancer...


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Your Price
$126.18 10MG
Discontinued

Not available outside of the UK & Ireland.

Application

Procarbazine, an antineoplastic alkylating agent, may be used to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an anticancer agent. It may be used to study new combination of anticancer drugs.

Procarbazine hydrochloride has been used to study its physicochemical property.

Biochem/physiol Actions

Procarbazine is an antineoplastic alkylating agent widely used in cancer chemotherapy in combination with other compounds. It has multiple mechanisms of action. Procarbazine inhibits protein, RNA and DNA synthesis in addition to being an alkylating agent.

Procarbazine is metabolized to azoprocarbazine either by cytochrome P450 enzyme and monoamine oxidase in an NADPH (nicotinamide adenine diphosphate) dependent or independent manner. It is considered neurotoxic. Procarbazine is used in combination with therapy for treating Hodgkin′s disease.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to tan
formpowder
InChI keyDERJYEZSLHIUKF-UHFFFAOYSA-N
InChI1S/C12H19N3O.ClH/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;/h4-7,9,13-14H,8H2,1-3H3,(H,15,16);1H
Quality Level100
SMILES stringCl.CNNCc1ccc(cc1)C(=O)NC(C)C
solubilityDMSO: ≥18 mg/mL
storage temp.2-8°C
Cas Number366-70-1
This product has met the following criteria to qualify for the following awards:



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